Sekiya Tooru, a 31-year-old researcher specializing in seawater desalination, finds his life irrevocably changed during a social studies field trip. While explaining his work to four high school students, a mysterious crystal appears. When one of the students, Yanagi, touches it, Tooru and the students are enveloped in light and transported to a pure white void.
There, a self-proclaimed God announces she has summoned the four young "heroes" to save her world from demons. Tooru, attempting to protect the students, is dismissed by the God, who claims adults cannot be granted skills. He is forcibly teleported away, leaving the panicked students behind. Tooru awakens alone in a dark, unfamiliar forest filled with strange, otherworldly plants. He worries about the students, assuming they've received special abilities, and resolves to find a way to return them to their world. His immediate goal is to survive and reach a town.
His first encounter is with a horned rabbit, which surprisingly attacks and injures his leg. A light-armored man appears, seemingly offering aid. Unable to understand the local language, Tooru trusts the man, who provides crude first aid and leads him out of the forest. However, this trust is betrayed when the man sells Tooru to a pot-bellied slave merchant in a bustling slave market. Tooru is thrown into a cell, realizing he's now a slave in a world where slavery is common and public, and various races like beast-humans and lizard-men exist.
Overwhelmed by the language barrier and his new status, Tooru is brought to the main stage of the slave market. He is mocked for being "skill-less" and unable to speak their language. Unbought, Tooru is condemned to the "Coliseum" (arena) as a gladiator. Humiliated and enraged, he vows to survive and defy those who mock him, developing a fierce determination to live.
In the gladiator cells, Tooru is given flimsy armor and a rusty sword. Unable to bring himself to kill with a blade, he uses his scientific ingenuity and past experience (baseball) to craft a makeshift slingshot from his handguard, clothes, and stones. He is led into a massive arena where an announcer incites the hostile crowd against "skill-users" and "heroes." Tooru's opponent is Oraid, a heavily armored "5th-grade gladiator." Tooru uses his slingshot to incapacitate Oraid by hitting his unprotected leg and then his neck. Under immense pressure from the bloodthirsty crowd, Tooru is forced to deliver the killing blow with Oraid's axe, a traumatic act that solidifies his resolve to survive.
However, his victory is met with brutal torture by the showman, who lost money betting on Tooru's death. Tooru is whipped and burned with a heated iron rod, enduring unimaginable pain. This ordeal transforms his will to survive into a burning desire for revenge, as he vows to kill the sadistic showman.
Severely injured, Tooru wakes in his cell to find Mina Garrett, a cat-eared beast-human slave gladiator, nursing his wounds. Tooru discovers he can now understand her, and she speaks a version of his language, having learned it from another "isekai-jin" she once helped. Mina, resigned to dying in an upcoming "group battle" where 30 slave gladiators will be hunted by cavalry, shares world-building information about races and magic. Tooru, desperate to survive and save Mina, asks about magic. He fails to activate lightning, wind, fire, or earth magic, but, as a water researcher, insists on trying water magic, which Mina dismisses as useless. Tooru chants "Mine" and successfully produces a small amount of water in his palm, revealing a rare aptitude for water magic. Mina explains this could free him and send him to a research institution.
Tooru is overjoyed but quickly realizes his freedom won't extend to Mina, who is branded as a rebellious slave. Refusing to abandon her, Tooru decides to master water magic for combat. Applying his scientific knowledge of atmospheric water vapor, he calculates how much water can be gathered from a given space. He successfully gathers a significant amount of water by imagining drawing from a larger area, realizing the world's mages likely failed due to a lack of understanding. Tooru, now determined to save Mina and revolutionize water magic, asks her to teach him more local language to further develop his combat-oriented water magic, vowing to prove its strength and change the world's perception.